Advances in developing therapeutic strategies for Alzheimer's disease
نویسندگان
چکیده
منابع مشابه
Advances in genetic therapeutic strategies for Duchenne muscular dystrophy
NEW FINDINGS What is the topic of this review? This review highlights recent progress in genetically based therapies targeting the primary defect of Duchenne muscular dystrophy. What advances does it highlight? Over the last two decades, considerable progress has been made in understanding the mechanisms underlying Duchenne muscular dystrophy, leading to the development of genetic therapies. Th...
متن کاملTherapeutic Strategies in Huntington's Disease
This article provides an overview of the therapeutic strategies, from ordinary classical drugs to the modern molecular strategy at experimental level, for Huntington's disease. The disease is characterized by choreic movements, psychiatric disorders, striatal atrophy with selective small neuronal loss, and autosomal dominant inheritance. The genetic abnormality is CAG expansion in huntingtin ge...
متن کاملGlucose Role in Treatment of Alzheimers’ Disease
1. Dong H, Csernansky JG (2009) Effects of Stress and Stress Hormones on Amyloidβ Protein and Plaque Deposition. J Alzheimers Dis 18: 459-469. 2. Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, et al. (2006) Plasma cortisol and progression of dementia in subjects with Alzheimer‐ type dementia. Am J Psychiatry 163: 2164-2169. 3. Swaab DF, Raadsheer FC, Endert E, Hofman MA, Kamphorst W, et al. ...
متن کاملEmerging Therapeutic Strategies in Alzheimer's Disease
Alzheimer’s disease (AD) is the most common cause of dementia in midto late-life. It currently affects about 10% of individuals older than 65 years old, counting for more than 25 million people in the world (Chiba et al., 2007; Huang and Mucke, 2012; Mattson, 2004). A century has passed since the famous neurologist Alois Alzheimer first described about a 51-year-old female patient with severe p...
متن کاملNeurodegenerative pathways in Parkinson's disease: therapeutic strategies.
Parkinson's disease (PD), considered one of the major neurological disorders, is characterized by the loss of dopaminergic neurons in the pars compacta of the substantia nigra and by the presence of intraneuronal cytoplasmic inclusions called Lewy bodies. The causes for degeneration of PD neurons remain unclear, however, recent findings contributed to clarify this issue. This review will discus...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2021
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2021.111623